Heparanase facilitates cell adhesion and spreading by clustering of cell surface heparan sulfate proteoglycans.
Heparanase is a heparan sulfate (HS) degrading endoglycosidase participating in Ginger Jar extracellular matrix degradation and remodeling.Apart of its well characterized enzymatic activity, heparanase was noted to exert also enzymatic-independent functions.Non-enzymatic activities of heparanase include enhanced adhesion of tumor-derived cells and